C11orf20 (TEX40) (NM_001039496) Human Mass Spec Standard

Specifications

Product Data
Description	C11orf20 MS Standard C13 and N15-labeled recombinant protein (NP_001034585)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC220639
Predicted MW	22.7 kDa
Protein Sequence	Sequence Link (showhide) >RC220639 representing NM_001039496 Red=Cloning site Green=Tags(s) MEEKPSKVSLKSSDRQGSDEESVHSDTRDLWTTTTLSQAQLNMPLSEVCEGFDEEGRNISKTRGWHSPGR GSLDEGYKASHKPEELDEHALVELELHRGSSMEINLGEKDTASQIEAEKSSSMSSLNIAKHMPHRAYWAE QQSRLPLPLMELMENEALEILTKALRSYQLGIGRDHFLTKELQRYIEGLKKRRSKRLYVN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001034585
RefSeq Size	764
RefSeq ORF	600
Synonyms	C11orf20; TEX40
Locus ID	25858
Cytogenetics	11q13.1
Summary	Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for a distribution of the CatSper complex in linear quadrilateral nanodomains along the flagellum, maximizing fertilization inside the mammalian female reproductive tract. Together with EFCAB9, associates with the CatSper channel pore and is required for the two-row structure of each single CatSper channel.[UniProtKB/Swiss-Prot Function]

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