HNF 4 alpha (HNF4A) (NM_178849) Human Recombinant Protein
CAT#: TP314914
Recombinant protein of human hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 1, 20 µg
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC214914 representing NM_178849
Red=Cloning site Green=Tags(s) MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGK HYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTR RSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCE LPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPSRSCR SMTMSMPTSKPSSSLTQMPRG TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 51.4 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_849180 |
| Locus ID | 3172 |
| UniProt ID | F1D8S2 |
| Refseq Size | 4707 |
| Cytogenetics | 20q13.12 |
| Refseq ORF | 1392 |
| Synonyms | FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF-14; TCF14 |
| Summary | The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012] |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Nuclear Hormone Receptor, Transcription Factors |
| Protein Pathways | Maturity onset diabetes of the young |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400161 | HNF4A HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
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| LC405861 | HNF4A HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
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| LC422283 | HNF4A HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
|
| LC422284 | HNF4A HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY400161 | Transient overexpression lysate of hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 2 |
CNY 4840.00 |
|
| LY405861 | Transient overexpression lysate of hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 3 |
CNY 4840.00 |
|
| LY422283 | Transient overexpression lysate of hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 5 |
CNY 4840.00 |
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| LY422284 | Transient overexpression lysate of hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 6 |
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| PH311443 | HNF4A MS Standard C13 and N15-labeled recombinant protein (NP_001025174) |
CNY 19520.00 |
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| PH314914 | HNF4A MS Standard C13 and N15-labeled recombinant protein (NP_849180) |
CNY 19520.00 |
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| PH316588 | HNF4A MS Standard C13 and N15-labeled recombinant protein (NP_001025175) |
CNY 19520.00 |
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| PH317863 | HNF4A MS Standard C13 and N15-labeled recombinant protein (NP_000448) |
CNY 19520.00 |
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| PH317924 | HNF4A MS Standard C13 and N15-labeled recombinant protein (NP_849181) |
CNY 19520.00 |
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| TP311443 | Recombinant protein of human hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 5, 20 µg |
CNY 2900.00 |
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| TP316588 | Recombinant protein of human hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 6, 20 µg |
CNY 2900.00 |
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| TP317863 | Recombinant protein of human hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 2, 20 µg |
CNY 2900.00 |
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| TP317924 | Recombinant protein of human hepatocyte nuclear factor 4, alpha (HNF4A), transcript variant 3, 20 µg |
CNY 2900.00 |
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