Collagen IX (COL9A1) (NM_001851) Human Recombinant Protein
CAT#: TP318130
Recombinant protein of human collagen, type IX, alpha 1 (COL9A1), transcript variant 1, 20 µg
View other "Collagen IX" proteins (7)
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CNY 2900.00
CNY 6650.00
| Cited in 2 publications. |
CNY 600.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC218130 representing NM_001851
Red=Cloning site Green=Tags(s) MKTCWKIPVFFFVCSFLEPWASAAVKRRPRFPVNSNSNGGNELCPKIRIGQDDLPGFDLISQFQVDKAAS RRAIQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQIQDSSGKE QVGIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKPRG PIDIDGFAVLGKLADNPQVSVPFELQWMLIHCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPP GPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPG SRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRS GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDG EPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK PGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGEL GPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPG PKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVI QEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK GERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQA GQRAFNKGPDP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 89.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_001842 |
| Locus ID | 1297 |
| UniProt ID | P20849 |
| Refseq Size | 3704 |
| Cytogenetics | 6q13 |
| Refseq ORF | 2763 |
| Synonyms | DJ149L1.1.2; EDM6; MED; STL4 |
| Summary | This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome |
Citations (2)
| The use of this Proteins has been cited in the following citations: |
|---|
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A SMOC2 variant inhibits BMP signaling by competitively binding to BMPR1B and causes growth plate defects
,Long, F;Shi, H;Li, P;Guo, S;Ma, Y;Wei, S;Li, Y;Gao, F;Gao, S;Wang, M;Duan, R;Wang, X;Yang, K;Sun, W;Li, X;Li, J;Liu, Q;,
Bone
,PubMed ID 33059102
[COL9A1]
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A variant in SMOC2, inhibiting BMP signaling by competitively binding to BMPR1B, causes multiple epiphyseal dysplasia
,Long, F;Li, L;Shi, H;Li, P;Guo, S;Ma, Y;Li, Y;Wei, S;,
BioRxiv
[COL9A1]
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Resources
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC409192 | COL9A1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC419709 | COL9A1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
|
| LY409192 | Transient overexpression lysate of collagen, type IX, alpha 1 (COL9A1), transcript variant 2 |
CNY 3080.00 |
|
| LY419709 | Transient overexpression lysate of collagen, type IX, alpha 1 (COL9A1), transcript variant 1 |
CNY 4840.00 |
|
| PH309473 | COL9A1 MS Standard C13 and N15-labeled recombinant protein (NP_511040) |
CNY 14250.00 |
|
| PH318130 | COL9A1 MS Standard C13 and N15-labeled recombinant protein (NP_001842) |
CNY 19520.00 |
|
| TP309473 | Recombinant protein of human collagen, type IX, alpha 1 (COL9A1), transcript variant 2, 20 µg |
CNY 2900.00 |
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